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Preparation and characterization of Alendronate depot microspheres based on novel poly(-ε-caprolactone)/Vitamin E TPGS copolymers

In the present study, new aledronate (AL) loaded microspheres were prepared with the use of polycaprolactone (PCL)/Vitamin E d-ɑ-tocopheryl poly(ethylene glycol) 1000 succinate (TPGS) copolymers. Specifically, PCL-TPGS copolymers, prepared at several PCL to TPGS ratios (namely, 90/10, 80/20, 70/30 a...

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Detalhes bibliográficos
Publicado no:Int J Pharm X
Main Authors: Koulouktsi, Christina, Nanaki, Stavroula, Barmpalexis, Panagiotis, Kostoglou, Margaritis, Bikiaris, Dimitrios
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733287/
https://ncbi.nlm.nih.gov/pubmed/31517279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpx.2019.100014
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