Integrative Genomic Characterization Identifies Molecular Subtypes of Lung Carcinoids

Lung carcinoids (LCs) are rare and slow growing primary lung neuroendocrine tumors. We performed targeted exome sequencing, mRNA sequencing and DNA methylation array analysis on macro-dissected lung carcinoids. Recurrent mutations were enriched for genes involved in covalent histone modification/chr...

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Gepubliceerd in:Cancer Res
Hoofdauteurs: Laddha, Saurabh V., da Silva, Edaise M., Robzyk, Kenneth, Untch, Brian R., Ke, Hua, Rekhtman, Natasha, Poirier, John T., Travis, William D., Tang, Laura H., Chan, Chang S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733269/
https://ncbi.nlm.nih.gov/pubmed/31300474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-0214
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