Enhancing Chondrogenesis and Mechanical Strength Retention in Physiologically Relevant Hydrogels with Incorporation of Hyaluronic Acid and Direct Loading of TGF-β

Cell-loaded hydrogels are frequently applied in cartilage tissue engineering for their biocompatibility, ease of application, and ability to conform to various defect sites. As a bioactive adjunct to the biomaterial, transforming growth factor beta (TGF-β) has been shown to be essential for cell dif...

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Veröffentlicht in:Acta Biomater
Hauptverfasser: Deng, Yuhao, Sun, Aaron X., Overholt, Kalon J., Yu, Gary Z., Fritch, Madalyn R., Alexander, Peter G., Shen, He, Tuan, Rocky S., Lin, Hang
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733255/
https://ncbi.nlm.nih.gov/pubmed/30458242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2018.11.022
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