Aldosterone impairs coronary adenosine-mediated vasodilation via reduced functional expression of Ca(2+)-activated K(+) channels

Elevated plasma aldosterone (Aldo) levels are associated with greater risk of cardiac ischemic events and cardiovascular mortality. Adenosine-mediated coronary vasodilation is a critical cardioprotective mechanism during ischemia; however, whether this response is impaired by increased Aldo is uncle...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Khan, Maloree, Meuth, Alex I., Brown, Scott M., Chandrasekar, Bysani, Bowles, Douglas K., Bender, Shawn B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732485/
https://ncbi.nlm.nih.gov/pubmed/31199187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00081.2019
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