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Embryonic stem cell-derived exosomes inhibit doxorubicin-induced TLR4-NLRP3-mediated cell death-pyroptosis

Doxorubicin (Dox)-induced cardiac side effects are regulated through increased oxidative stress and apoptosis. However, it remains unknown whether Dox induces the specific inflammatory-mediated form of cell death called pyroptosis. The current study is undertaken to determine whether Dox induces pyr...

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Pubblicato in:Am J Physiol Heart Circ Physiol
Autori principali: Tavakoli Dargani, Zahra, Singla, Dinender K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732475/
https://ncbi.nlm.nih.gov/pubmed/31172809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00056.2019
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