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New PRPS1 variant p.(Met68Leu) located in the dimerization area identified in a French CMTX5 patient

BACKGROUND: CMTX5 is characterized by peripheral neuropathy, early‐onset sensorineural hearing impairment, and optic neuropathy. Only seven variants have been reported and no genotype‐phenotype correlations have yet been established. PRPS1 has a crystallographic structure, as it is composed of three...

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Dettagli Bibliografici
Pubblicato in:Mol Genet Genomic Med
Autori principali: Lerat, Justine, Magdelaine, Corinne, Derouault, Paco, Beauvais‐Dzugan, Hélène, Bieth, Eric, Acket, Blandine, Arne‐Bes, Marie‐Christine, Sturtz, Franck, Lia, Anne‐Sophie
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732271/
https://ncbi.nlm.nih.gov/pubmed/31338985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.875
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