TGF-β1 and TNF-α synergistically induce epithelial to mesenchymal transition of breast cancer cells by enhancing TAK1 activation

TGF-β1 is a main inducer of epithelial to mesenchymal transition (EMT). However, many breast cancer cells are not sensitive to the EMT induction by TGF-β1 alone. So far, the mechanisms underlying the induction of TGF-β1-insensitive breast cancer cells remains unclear. Here we report that TNF-α can i...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Cell Commun Signal
Auteurs principaux: Liao, Sheng-Jun, Luo, Jing, Li, Dong, Zhou, Yuan-Hong, Yan, Bin, Wei, Jing-Jing, Tu, Jian-Cheng, Li, Yi-Rong, Zhang, Gui-Mei, Feng, Zuo-Hua
Format: Artigo
Langue:Inglês
Publié: Springer Netherlands 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732143/
https://ncbi.nlm.nih.gov/pubmed/30739244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-019-00508-8
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