Chronic memantine decreases nicotine self-administration in rats

Neurobehavioral bases of tobacco addiction and nicotine reinforcement are complex, involving more than only nicotinic cholinergic or dopaminergic systems. Memantine is an NMDA glutamate antagonist used to improve cognitive function in people with Alzheimer’s disease. Glutamate may be an important co...

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Publicat a:Eur J Pharmacol
Autors principals: Levin, Edward D., Wells, Corinne, Yao, Leah, Guo, Wendi, Nangia, Anica, Howard, Sarah, Pippen, Erica, Hawkey, Andrew B., Rose, Jed E., Rezvani, Amir H.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732003/
https://ncbi.nlm.nih.gov/pubmed/31421087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2019.172592
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