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MicroRNA-765 sensitizes osteosarcoma cells to cisplatin via downregulating APE1 expression

OBJECTIVES: Osteosarcoma (OS) is the most common bone cancer diagnosed in children and adolescents. Expression of APE1 is commonly increased in OS, and this is negatively correlated with a sensitivity to platinum and a favorable prognosis. However, the mechanism underlying high APE1 expression in OS...

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Vydáno v:Onco Targets Ther
Hlavní autoři: Liang, Wei, Li, Chongyi, Li, Mengxia, Wang, Dong, Zhong, Zhaoyang
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731985/
https://ncbi.nlm.nih.gov/pubmed/31564904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S194800
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