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Proteomic method to extract, concentrate, digest and enrich peptides from fossils with coloured (humic) substances for mass spectrometry analyses

Humic substances are breakdown products of decaying organic matter that co-extract with proteins from fossils. These substances are difficult to separate from proteins in solution and interfere with analyses of fossil proteomes. We introduce a method combining multiple recent advances in extraction...

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Foilsithe in:R Soc Open Sci
Main Authors: Schroeter, Elena R., Blackburn, Kevin, Goshe, Michael B., Schweitzer, Mary H.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Royal Society 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731700/
https://ncbi.nlm.nih.gov/pubmed/31598217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.181433
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