CPEB3 inhibits translation of mRNA targets by localizing them to P bodies

Protein synthesis is crucial for the maintenance of long-term memory-related synaptic plasticity. The cytoplasmic polyadenylation element-binding protein 3 (CPEB3) regulates the translation of several mRNAs important for long-term synaptic plasticity in the hippocampus. In previous studies, we found...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Ford, Lenzie, Ling, Emi, Kandel, Eric R., Fioriti, Luana
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731686/
https://ncbi.nlm.nih.gov/pubmed/31416913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1815275116
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