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Peroxidase evolution in white-rot fungi follows wood lignin evolution in plants

A comparison of sequenced Agaricomycotina genomes suggests that efficient degradation of wood lignin was associated with the appearance of secreted peroxidases with a solvent-exposed catalytic tryptophan. This hypothesis is experimentally demonstrated here by resurrecting ancestral fungal peroxidase...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Ayuso-Fernández, Iván, Rencoret, Jorge, Gutiérrez, Ana, Ruiz-Dueñas, Francisco Javier, Martínez, Angel T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731631/
https://ncbi.nlm.nih.gov/pubmed/31427536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1905040116
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