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Computational Insights into Avidity of Polymeric Multivalent Binders

Multivalent binding interactions are commonly found throughout biology to enhance weak monovalent binding such as between glycoligands and protein receptors. Designing multivalent polymers to bind to viruses and toxic proteins is a promising avenue for inhibiting their attachment and subsequent infe...

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Bibliografiske detaljer
Udgivet i:Biophys J
Main Authors: Zumbro, Emiko, Witten, Jacob, Alexander-Katz, Alfredo
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731389/
https://ncbi.nlm.nih.gov/pubmed/31400918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.07.026
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