IL-27 posttranslationally regulates Y-box binding protein-1 to inhibit HIV-1 replication in human CD4(+) T cells

IL-27 is known as an antiviral cytokine that inhibits HIV, hepatitis C virus, and other viruses. We have previously demonstrated that, IL-27 posttreatment after HIV-infection inhibits viral replication in primary CD4(+) T cells. DESIGN: Here, we evaluated the anti-HIV effect of IL-27 pretreatment in...

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Dettagli Bibliografici
Pubblicato in:AIDS
Autori principali: Poudyal, Deepak, Yang, Jun, Chen, Qian, Goswami, Suranjana, Adelsberger, Joseph W., Das, Sudipto, Herman, Andrew, Hornung, Ronald L., Andresson, Thorkell, Imamichi, Tomozumi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2019
Soggetti:
Basic Science
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731144/
https://ncbi.nlm.nih.gov/pubmed/31274540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000002288
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