Liposomal delivery of ferritin heavy chain 1 (FTH1) siRNA in patient xenograft derived glioblastoma initiating cells suggests different sensitivities to radiation and distinct survival mechanisms

Elevated expression of the iron regulatory protein, ferritin heavy chain 1 (FTH1), is increasingly being associated with high tumor grade and poor survival outcomes in glioblastoma. Glioma initiating cells (GICs), a small population of stem-like cells implicated in therapeutic resistance and gliobla...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Ravi, Vagisha, Madhankumar, Achuthamangalam B., Abraham, Thomas, Slagle-Webb, Becky, Connor, James R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730865/
https://ncbi.nlm.nih.gov/pubmed/31491006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221952
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