Identification and characterization of RSIY-11, a novel seminal peptide derived from semenogelin-1, which acts as a neutral endopeptidase inhibitor modulating sperm motility

PURPOSE: Based on prior reports demonstrating that neutral endopeptidase (NEP) inhibitors increase sperm motility, the goal of our studies was to identify endogenous seminal peptides that inhibit NEP and investigate their potential effect on sperm motility. METHODS: Peptidomic analysis was performed...

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Veröffentlicht in:J Assist Reprod Genet
Hauptverfasser: Fritz, Rani, Mukherjee, Amarnath, Zaghi, Sahar, Agalliu, Ilir, Jindal, Sangita, Tashima, Alexandre K., Fricker, Lloyd D., Davies, Kelvin P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2019
Schlagworte:
Gamete Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730740/
https://ncbi.nlm.nih.gov/pubmed/31346917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-019-01524-8
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