Identification of Aloperine as an anti-apoptotic Bcl2 protein inhibitor in glioma cells

OBJECTIVE: Aloperine (ALO), an alkaloid isolated from the leaves of Sophora alopecuroides, has been suggested to exhibit anti-inflammatory and anti-tumor properties and is traditionally used to treat various human diseases, including cancer. However, limited information is available about the mechan...

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Bibliographic Details
Published in:PeerJ
Main Authors: Xu, Zhijie, Wang, Xiang, Chen, Xi, Zeng, Shuangshuang, Qian, Long, Wei, Jie, Gong, Zhicheng, Yan, Yuanliang
Format: Artigo
Language:Inglês
Published: PeerJ Inc. 2019
Subjects:
Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730530/
https://ncbi.nlm.nih.gov/pubmed/31534865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.7652
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