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Interaction between the Corticotropin-Releasing Factor System and Hypocretins (Orexins): A Novel Circuit Mediating Stress Response

The hypothalamic neuropeptides hypocretins (orexins) play a crucial role in the stability of arousal and alertness. We tested whether the hypocretinergic system is a critical component of the stress response activated by the corticotropin-releasing factor (CRF). Our results show that CRF-immunoreact...

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Pubblicato in:J Neurosci
Autori principali: Winsky-Sommerer, Raphaëlle, Yamanaka, Akihiro, Diano, Sabrina, Borok, Erzsebet, Roberts, Amanda J., Sakurai, Takeshi, Kilduff, Thomas S., Horvath, Tamas L., de Lecea, Luis
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730356/
https://ncbi.nlm.nih.gov/pubmed/15601950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3459-04.2004
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