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Enhancement of Working Memory in Aged Monkeys by a Sensitizing Regimen of Dopamine D(1) Receptor Stimulation

A natural consequence of aging is a loss of dopamine function and associated deficits in working memory in both human and nonhuman primates. Specifically, deficiency of D(1) receptor signaling has been implicated in age-related cognitive decline. Here, we report that an intermittent, sensitizing reg...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Castner, Stacy A., Goldman-Rakic, Patricia S.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730346/
https://ncbi.nlm.nih.gov/pubmed/14960617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3987-03.2004
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