The Mental Retardation Protein PAK3 Contributes to Synapse Formation and Plasticity in Hippocampus

Mutations of the gene coding for PAK3 (p21-activated kinase 3) are associated with X-linked, nonsyndromic forms of mental retardation (MRX) in which the only distinctive clinical feature is the cognitive deficit. The mechanisms through which PAK3 mutation produces the mental handicap remain unclear,...

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Pubblicato in:J Neurosci
Autori principali: Boda, Bernadett, Alberi, Stefano, Nikonenko, Irina, Node-Langlois, Roxanne, Jourdain, Pascal, Moosmayer, Marlyse, Parisi-Jourdain, Lorena, Muller, Dominique
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2004
Soggetti:
Development/Plasticity/Repair
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730202/
https://ncbi.nlm.nih.gov/pubmed/15574732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2931-04.2004
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