Interferon-γ Induced Medulloblastoma in the Developing Cerebellum

We have generated a mouse model system with a high incidence of medulloblastoma, a malignant neoplasm believed to arise from immature precursors of cerebellar granule neurons. These animals ectopically express interferon-γ (IFN-γ) in astrocytes in the CNS in a controlled manner, exploiting the tetra...

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Bibliografiska uppgifter
I publikationen:J Neurosci
Huvudupphovsmän: Lin, Wensheng, Kemper, April, McCarthy, Ken D., Pytel, Peter, Wang, Jian-Ping, Campbell, Iain L., Utset, Manuel F., Popko, Brian
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2004
Ämnen:
Neurobiology of Disease
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730177/
https://ncbi.nlm.nih.gov/pubmed/15537876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2604-04.2004
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