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Na-K-Cl Cotransporter-Mediated Intracellular Na(+) Accumulation Affects Ca(2+) Signaling in Astrocytes in an In Vitro Ischemic Model

Na-K-Cl cotransporter isoform 1 (NKCC1) plays an important role in maintenance of intracellular Na(+), K(+), and Cl(-) levels in astrocytes. We propose that NKCC1 may contribute to perturbations of ionic homeostasis in astrocytes under ischemic conditions. After 3-8 hr of oxygen and glucose deprivat...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Lenart, Brett, Kintner, Douglas B., Shull, Gary E., Sun, Dandan
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730155/
https://ncbi.nlm.nih.gov/pubmed/15509746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2569-04.2004
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