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Spontaneous Withdrawal from the Triazolobenzodiazepine Alprazolam Increases Cortical Corticotropin-Releasing Factor mRNA Expression

Corticotropin-releasing factor (CRF) is the major physiologic regulator of the hypothalamic-pituitary-adrenal (HPA) axis and plays a key role in coordinating the mammalian stress response. Substantial data implicates hyperactivity of CRF neuronal systems in the pathophysiology of depression and anxi...

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Vydáno v:J Neurosci
Hlavní autoři: Skelton, Kelly H., Nemeroff, Charles B., Owens, Michael J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2004
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730084/
https://ncbi.nlm.nih.gov/pubmed/15496666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1737-04.2004
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