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The Central Fragment of Reelin, Generated by Proteolytic Processing In Vivo, Is Critical to Its Function during Cortical Plate Development

Reelin is a large extracellular protein that controls cortical development. It binds to lipoprotein receptors very-low-density lipoprotein receptor and apolipoprotein-E receptor type 2, thereby inducing phosphorylation of the adapter Dab1. In vivo, Reelin is cleaved into three fragments, but their r...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Jossin, Yves, Ignatova, Nina, Hiesberger, Thomas, Herz, Joachim, Lambert de Rouvroit, Catherine, Goffinet, André M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2004
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730001/
https://ncbi.nlm.nih.gov/pubmed/14724251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3408-03.2004
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