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The Effects of Vesicular Volume on Secretion through the Fusion Pore in Exocytotic Release from PC12 Cells

Many spikes in amperometric records of exocytosis events initially exhibit a prespike feature, or foot, which represents a steady-state flux of neurotransmitter through a stable fusion pore spanning both the vesicle and plasma membranes and connecting the vesicle lumen to the extracellular fluid. He...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Sombers, L. A., Hanchar, H. J., Colliver, T. L., Wittenberg, N., Cans, A., Arbault, S., Amatore, C., Ewing, A. G.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2004
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729980/
https://ncbi.nlm.nih.gov/pubmed/14724228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1119-03.2004
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