Brain-Derived Neurotrophic Factor Induces Hyperexcitable Reentrant Circuits in the Dentate Gyrus

Aberrant sprouting and synaptic reorganization of the mossy fiber (MF) axons are commonly found in the hippocampus of temporal lobe epilepsy patients and result in the formation of excitatory feedback loops in the dentate gyrus, a putative cellular basis for recurrent epileptic seizures. Using ex vi...

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Vydáno v:J Neurosci
Hlavní autoři: Koyama, Ryuta, Yamada, Maki K., Fujisawa, Shigeyoshi, Katoh-Semba, Ritsuko, Matsuki, Norio, Ikegaya, Yuji
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2004
Témata:
Development/Plasticity/Repair
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729760/
https://ncbi.nlm.nih.gov/pubmed/15317847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2045-04.2004
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