Brain-Derived Neurotrophic Factor Induces Hyperexcitable Reentrant Circuits in the Dentate Gyrus

Aberrant sprouting and synaptic reorganization of the mossy fiber (MF) axons are commonly found in the hippocampus of temporal lobe epilepsy patients and result in the formation of excitatory feedback loops in the dentate gyrus, a putative cellular basis for recurrent epileptic seizures. Using ex vi...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Koyama, Ryuta, Yamada, Maki K., Fujisawa, Shigeyoshi, Katoh-Semba, Ritsuko, Matsuki, Norio, Ikegaya, Yuji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2004
Schlagworte:
Development/Plasticity/Repair
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729760/
https://ncbi.nlm.nih.gov/pubmed/15317847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2045-04.2004
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