Brain-Derived Neurotrophic Factor Induces Hyperexcitable Reentrant Circuits in the Dentate Gyrus

Aberrant sprouting and synaptic reorganization of the mossy fiber (MF) axons are commonly found in the hippocampus of temporal lobe epilepsy patients and result in the formation of excitatory feedback loops in the dentate gyrus, a putative cellular basis for recurrent epileptic seizures. Using ex vi...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Koyama, Ryuta, Yamada, Maki K., Fujisawa, Shigeyoshi, Katoh-Semba, Ritsuko, Matsuki, Norio, Ikegaya, Yuji
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2004
Fag:
Development/Plasticity/Repair
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729760/
https://ncbi.nlm.nih.gov/pubmed/15317847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2045-04.2004
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