Identification of Ectodomain Regions Contributing to Gating, Deactivation, and Resensitization of Purinergic P2X Receptors

The P2X receptors (P2XRs) are a family of ligand-gated channels activated by extracellular ATP through a sequence of conformational transitions between closed, open, and desensitized states. In this study, we examined the dependence of the activity of P2XRs on ectodomain structure and agonist potenc...

Full description

Saved in:
Bibliographic Details
Published in:J Neurosci
Main Authors: Zemkova, Hana, He, Mu-Lan, Koshimizu, Taka-aki, Stojilkovic, Stanko S.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2004
Subjects:
Cellular/Molecular
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729606/
https://ncbi.nlm.nih.gov/pubmed/15295032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1471-04.2004
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items