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Wnt Signaling Mutants Have Decreased Dentate Granule Cell Production and Radial Glial Scaffolding Abnormalities

LRP6 mutant mice have generalized defects in the Wnt/β-catenin signaling pathway because of the crucial function of LRP6 as a Wnt signaling co-receptor (Pinson et al., 2000). We examined the hippocampal phenotype of single LRP6 mutant mice as well as LRP6/Lef1 double mutant mice. LRP6 mutants had re...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Zhou, Cheng-Ji, Zhao, Chunjie, Pleasure, Samuel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729560/
https://ncbi.nlm.nih.gov/pubmed/14715945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4071-03.2004
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