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Activation of the Phosphoinositide 3-Kinase-Akt-Mammalian Target of Rapamycin Signaling Pathway Is Required for Metabotropic Glutamate Receptor-Dependent Long-Term Depression

Hippocampal long-term depression (LTD) is a long-lasting decrease in synaptic strength that is most commonly studied at glutamatergic inputs to pyramidal cells in hippocampal area CA1. Activation of G-protein-coupled group I (including types 1 and 5) metabotropic glutamate receptors (mGluRs) by the...

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Библиографические подробности
Опубликовано в: :J Neurosci
Главные авторы: Hou, Lingfei, Klann, Eric
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2004
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729543/
https://ncbi.nlm.nih.gov/pubmed/15254091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0995-04.2004
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