Mutations in Caenorhabditis elegans Cytoplasmic Dynein Components Reveal Specificity of Neuronal Retrograde Cargo

We describe Caenorhabditis elegans dynein complex mutants, which misaccumulate synaptic proteins at the ends of neuronal processes. Ultrastructural analysis revealed irregularly sized vesicles that likely represent accumulation of cargo. We propose that synaptobrevin, synaptotagmin, and UNC-104 are...

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Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Koushika, Sandhya P., Schaefer, Anneliese M., Vincent, Rose, Willis, John H., Bowerman, Bruce, Nonet, Michael L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2004
Materias:
Cellular/Molecular
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729415/
https://ncbi.nlm.nih.gov/pubmed/15102906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5039-03.2004
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