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Mutations in Caenorhabditis elegans Cytoplasmic Dynein Components Reveal Specificity of Neuronal Retrograde Cargo

We describe Caenorhabditis elegans dynein complex mutants, which misaccumulate synaptic proteins at the ends of neuronal processes. Ultrastructural analysis revealed irregularly sized vesicles that likely represent accumulation of cargo. We propose that synaptobrevin, synaptotagmin, and UNC-104 are...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Koushika, Sandhya P., Schaefer, Anneliese M., Vincent, Rose, Willis, John H., Bowerman, Bruce, Nonet, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729415/
https://ncbi.nlm.nih.gov/pubmed/15102906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5039-03.2004
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