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Role of the α1G T-Type Calcium Channel in Spontaneous Absence Seizures in Mutant Mice

Alterations in thalamic T-type Ca(2+) channels are thought to contribute to the pathogenesis of absence seizures. Here, we found that mice with a null mutation for the pore-forming α1A subunits of P/Q-type channels (α1A(–/–) mice) were prone to absence seizures characterized by typical spike-and-wav...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Song, Inseon, Kim, Daesoo, Choi, Soonwook, Sun, Minjeong, Kim, Yeongin, Shin, Hee-Sup
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729205/
https://ncbi.nlm.nih.gov/pubmed/15175395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5546-03.2004
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