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Autoimmune receptor encephalitis in mice induced by active immunization with conformationally-stabilized holoreceptors

Autoimmunity to membrane proteins in the central nervous system has been increasingly recognized as a cause of neuropsychiatric disease. A key recent development was the discovery of autoantibodies to N-methyl-D-aspartate (NMDA) receptors in some cases of encephalitis, characterized by cognitive cha...

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Bibliographic Details
Published in:Sci Transl Med
Main Authors: Jones, Brian E., Tovar, Kenneth R, Goehring, April, Jalali-Yazdi, Farzad, Okada, Nana J., Gouaux, Eric, Westbrook, Gary L.
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729143/
https://ncbi.nlm.nih.gov/pubmed/31292262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaw0044
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