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Optimizing gentamicin conventional and extended interval dosing in neonates using Monte Carlo simulation – a retrospective study
BACKGROUND: Although aminoglycosides are routinely used in neonates, controversy exists regarding empiric dosing regimens. The objectives were to determine gentamicin pharmacokinetics in neonates, and develop initial mg/kg dosing recommendations that optimized target peak and trough concentration at...
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| Publicado en: | BMC Pediatr |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6729057/ https://ncbi.nlm.nih.gov/pubmed/31492162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12887-019-1676-3 |
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