Optimizing gentamicin conventional and extended interval dosing in neonates using Monte Carlo simulation – a retrospective study

BACKGROUND: Although aminoglycosides are routinely used in neonates, controversy exists regarding empiric dosing regimens. The objectives were to determine gentamicin pharmacokinetics in neonates, and develop initial mg/kg dosing recommendations that optimized target peak and trough concentration at...

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Bibliografische gegevens
Gepubliceerd in:BMC Pediatr
Hoofdauteurs: Bergenwall, Monique, Walker, Sandra A. N., Elligsen, Marion, Iaboni, Dolores C., Findlater, Carla, Seto, Winnie, Ng, Eugene
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2019
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729057/
https://ncbi.nlm.nih.gov/pubmed/31492162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12887-019-1676-3
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