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Hyperactivity, dopaminergic abnormalities, iron deficiency and anemia in an in vivo opioid receptors knockout mouse: Implications for the Restless Legs Syndrome

Previous studies have uncovered a potential role of the opioid system in iron hemostasis and dopamine metabolism. Abnormalities in both of these systems have been noted in human RLS. Autopsy studies of human RLS have shown an endogenous opioid deficiency in the thalamus. Opioids, particularly prolon...

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Detalles Bibliográficos
Publicado en:Behav Brain Res
Main Authors: Lyu, Shangru, DeAndrade, Mark P., Mueller, Stefan, Oksche, Alexander, Walters, Arthur S., Li, Yuqing
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728912/
https://ncbi.nlm.nih.gov/pubmed/31376441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2019.112123
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