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Slow degradation in phagocytic astrocytes can be enhanced by lysosomal acidification

Inefficient lysosomal degradation is central in the development of various brain disorders, but the underlying mechanisms and the involvement of different cell types remains elusive. We have previously shown that astrocytes effectively engulf dead cells, but then store, rather than degrade the inges...

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Detalhes bibliográficos
Publicado no:Glia
Main Authors: Lööv, Camilla, Mitchell, Claire H., Simonsson, Martin, Erlandsson, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728804/
https://ncbi.nlm.nih.gov/pubmed/26095880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22873
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