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Slow degradation in phagocytic astrocytes can be enhanced by lysosomal acidification

Inefficient lysosomal degradation is central in the development of various brain disorders, but the underlying mechanisms and the involvement of different cell types remains elusive. We have previously shown that astrocytes effectively engulf dead cells, but then store, rather than degrade the inges...

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Bibliographic Details
Published in:Glia
Main Authors: Lööv, Camilla, Mitchell, Claire H., Simonsson, Martin, Erlandsson, Anna
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728804/
https://ncbi.nlm.nih.gov/pubmed/26095880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22873
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