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Slow degradation in phagocytic astrocytes can be enhanced by lysosomal acidification
Inefficient lysosomal degradation is central in the development of various brain disorders, but the underlying mechanisms and the involvement of different cell types remains elusive. We have previously shown that astrocytes effectively engulf dead cells, but then store, rather than degrade the inges...
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Published in: | Glia |
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Main Authors: | , , , |
Format: | Artigo |
Language: | Inglês |
Published: |
2015
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6728804/ https://ncbi.nlm.nih.gov/pubmed/26095880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22873 |
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