Trastuzumab-Coated Nanoparticles Loaded With Docetaxel for Breast Cancer Therapy

Docetaxel (DTX) is commonly used for breast cancer treatment. Tween 80 used for DTX dissolution in its clinical formulation causes severe hypersensitivity and other adverse reactions. In this study, trastuzumab (Tmab)-coated lipid-polymer hybrid nanoparticles (PLNs) were prepared, composed of poly (...

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Publicat a:Dose Response
Autors principals: Zhang, Xueyan, Liu, Jiaxin, Li, Xiangyu, Li, Fang, Lee, Robert J., Sun, Fengying, Li, Youxin, Liu, Zongyu, Teng, Lesheng
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2019
Matèries:
Nanotechnology and Microtechnology in Drug Delivery Systems
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728688/
https://ncbi.nlm.nih.gov/pubmed/31523204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1559325819872583
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