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Rosiglitazone Regulates TLR4 and Rescues HO-1 and NRF2 Expression in Myometrial and Decidual Macrophages in Inflammation-Induced Preterm Birth

INTRODUCTION: Elevated inflammation accounts for approximately 30% of preterm birth (PTB) cases. We previously reported that targeting the peroxisome proliferator–activated receptor gamma (PPARγ) pathway reduced the incidence of PTB in the mouse model of endotoxin-induced PTB. The PPARγ has proven a...

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Detalhes bibliográficos
Publicado no:Reprod Sci
Main Authors: Kadam, Leena, Gomez-Lopez, Nardhy, Mial, Tara N., Kohan-Ghadr, Hamid-Reza, Drewlo, Sascha
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728562/
https://ncbi.nlm.nih.gov/pubmed/28322133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719117697128
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