Ivacaftor, a Cystic Fibrosis Transmembrane Conductance Regulator Potentiator, Enhances Ciprofloxacin Activity Against Pseudomonas aeruginosa

BACKGROUND: Methods to improve the clinical efficacy of currently available antibiotics against multidrug resistant bacteria in cystic fibrosis (CF) chronic rhinosinusitis (CRS) are greatly needed. Ivacaftor, a cystic fibrosis transmembrane conductance regulator potentiator, was recently identified...

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Bibliographic Details
Published in:Am J Rhinol Allergy
Main Authors: Cho, Do-Yeon, Lim, Dong Jin, Mackey, Calvin, Skinner, Daniel, Zhang, Shaoyan, McCormick, Justin, Woodworth, Bradford A.
Format: Artigo
Language:Inglês
Published: SAGE Publications 2018
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728449/
https://ncbi.nlm.nih.gov/pubmed/30585080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1945892418815615
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