Electrophysiological evaluation of extracellular spermine and alkaline pH on synaptic human GABA(A) receptors

Polyamines have fundamental roles in brain homeostasis as key modulators of cellular excitability. Several studies have suggested alterations in polyamine metabolism in stress related disorders, suicide, depression, and neurodegeneration, making the pharmacological modulation of polyamines a highly...

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Publicado en:Transl Psychiatry
Main Authors: Limon, A., Delbruck, E., Yassine, A., Pandya, D., Myers, R. M., Barchas, J. D., Lee, F., Schatzberg, Watson, S. J., Akil, H., Bunney, W. E., Vawter, M. P., Sequeira, A.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728327/
https://ncbi.nlm.nih.gov/pubmed/31488811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-019-0551-1
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