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Electrophysiological evaluation of extracellular spermine and alkaline pH on synaptic human GABA(A) receptors

Polyamines have fundamental roles in brain homeostasis as key modulators of cellular excitability. Several studies have suggested alterations in polyamine metabolism in stress related disorders, suicide, depression, and neurodegeneration, making the pharmacological modulation of polyamines a highly...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Limon, A., Delbruck, E., Yassine, A., Pandya, D., Myers, R. M., Barchas, J. D., Lee, F., Schatzberg, Watson, S. J., Akil, H., Bunney, W. E., Vawter, M. P., Sequeira, A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728327/
https://ncbi.nlm.nih.gov/pubmed/31488811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-019-0551-1
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