Evolution of intron splicing towards optimized gene expression is based on various Cis- and Trans-molecular mechanisms

Splicing expands, reshapes, and regulates the transcriptome of eukaryotic organisms. Despite its importance, key questions remain unanswered, including the following: Can splicing evolve when organisms adapt to new challenges? How does evolution optimize inefficiency of introns’ splicing and of the...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS Biol
Auteurs principaux: Frumkin, Idan, Yofe, Ido, Bar-Ziv, Raz, Gurvich, Yonat, Lu, Yen-Yun, Voichek, Yoav, Towers, Ruth, Schirman, Dvir, Krebber, Heike, Pilpel, Yitzhak
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728054/
https://ncbi.nlm.nih.gov/pubmed/31442222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000423
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