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Centromere-Proximal Meiotic Crossovers in Drosophila melanogaster Are Suppressed by Both Highly Repetitive Heterochromatin and Proximity to the Centromere

Crossovers are essential in meiosis of most organisms to ensure the proper segregation of chromosomes, but improper placement of crossovers can result in nondisjunction and aneuploidy in progeny. In particular, crossovers near the centromere can cause nondisjunction. Centromere-proximal crossovers a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genetics
Prif Awduron: Hartmann, Michaelyn, Umbanhowar, James, Sekelsky, Jeff
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Genetics Society of America 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727794/
https://ncbi.nlm.nih.gov/pubmed/31345993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302509
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