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Centromere-Proximal Meiotic Crossovers in Drosophila melanogaster Are Suppressed by Both Highly Repetitive Heterochromatin and Proximity to the Centromere

Crossovers are essential in meiosis of most organisms to ensure the proper segregation of chromosomes, but improper placement of crossovers can result in nondisjunction and aneuploidy in progeny. In particular, crossovers near the centromere can cause nondisjunction. Centromere-proximal crossovers a...

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Bibliografiske detaljer
Udgivet i:Genetics
Main Authors: Hartmann, Michaelyn, Umbanhowar, James, Sekelsky, Jeff
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727794/
https://ncbi.nlm.nih.gov/pubmed/31345993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302509
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