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The Drosophila Afadin and ZO-1 homologues Canoe and Polychaetoid act in parallel to maintain epithelial integrity when challenged by adherens junction remodeling

During morphogenesis, cells must change shape and move without disrupting tissue integrity. This requires cell–cell junctions to allow dynamic remodeling while resisting forces generated by the actomyosin cytoskeleton. Multiple proteins play roles in junctional–cytoskeletal linkage, but the mechanis...

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Publicado en:Mol Biol Cell
Autores principales: Manning, Lathiena A., Perez-Vale, Kia Z., Schaefer, Kristina N., Sewell, Mycah T., Peifer, Mark
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727765/
https://ncbi.nlm.nih.gov/pubmed/31188739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-04-0209
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