Clathrin and clathrin adaptor AP-1 control apical trafficking of megalin in the biosynthetic and recycling routes

Megalin (gp330, LRP-2) is a protein structurally related to the low-density lipoprotein receptor family that displays a large luminal domain with multiligand binding properties. Megalin localizes to the apical surface of multiple epithelia, where it participates in endocytosis of a variety of ligand...

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Bibliografiska uppgifter
I publikationen:Mol Biol Cell
Huvudupphovsmän: Gravotta, Diego, Perez Bay, Andres, Jonker, Caspar T. H., Zager, Patrick J., Benedicto, Ignacio, Schreiner, Ryan, Caceres, Paulo S., Rodriguez-Boulan, Enrique
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 2019
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727755/
https://ncbi.nlm.nih.gov/pubmed/31091172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-12-0811
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