Noninvasive and Quantitative Monitoring of the Distributions and Kinetics of MicroRNA-Targeting Molecules in Vivo by Positron Emission Tomography

[Image: see text] MicroRNAs (miRNAs) are endogenous, small, noncoding ribonucleic acids (RNAs) that bind to the 3′ untranslated regions of messenger RNAs (mRNAs) and induce translational repression or mRNA degradation. Although numerous studies have reported that miRNAs are of potential use for dise...

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Publicat a:Mol Pharm
Autors principals: Mäkilä, Jussi, Kiviniemi, Anu, Saanijoki, Tiina, Liljenbäck, Heidi, Käkelä, Meeri, Jadhav, Satish, Poijärvi-Virta, Päivi, Lönnberg, Harri, Laitala-Leinonen, Tiina, Virta, Pasi, Roivainen, Anne
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2019
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727608/
https://ncbi.nlm.nih.gov/pubmed/30865461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.8b01169
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