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Influence of low-dose radiation on abscopal responses in patients receiving high-dose radiation and immunotherapy

BACKGROUND: Preclinical evidence suggests that low-dose radiation may overcome the inhibitory effects of the tumor stroma and improve a tumor’s response to immunotherapy, when combined with high-dose radiation to another tumor. The aim of this study was to evaluate tumor responses to this combinatio...

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Publicado en:J Immunother Cancer
Autores principales: Menon, Hari, Chen, Dawei, Ramapriyan, Rishab, Verma, Vivek, Barsoumian, Hampartsoum B., Cushman, Taylor R., Younes, Ahmed I., Cortez, Maria A., Erasmus, Jeremy J., de Groot, Patricia, Carter, Brett W., Hong, David S., Glitza, Isabella C., Ferrarotto, Renata, Altan, Mehmet, Diab, Adi, Chun, Stephen G., Heymach, John V., Tang, Chad, Nguyen, Quynh N., Welsh, James W.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727581/
https://ncbi.nlm.nih.gov/pubmed/31484556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0718-6
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