Influence of low-dose radiation on abscopal responses in patients receiving high-dose radiation and immunotherapy

BACKGROUND: Preclinical evidence suggests that low-dose radiation may overcome the inhibitory effects of the tumor stroma and improve a tumor’s response to immunotherapy, when combined with high-dose radiation to another tumor. The aim of this study was to evaluate tumor responses to this combinatio...

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Vydáno v:J Immunother Cancer
Hlavní autoři: Menon, Hari, Chen, Dawei, Ramapriyan, Rishab, Verma, Vivek, Barsoumian, Hampartsoum B., Cushman, Taylor R., Younes, Ahmed I., Cortez, Maria A., Erasmus, Jeremy J., de Groot, Patricia, Carter, Brett W., Hong, David S., Glitza, Isabella C., Ferrarotto, Renata, Altan, Mehmet, Diab, Adi, Chun, Stephen G., Heymach, John V., Tang, Chad, Nguyen, Quynh N., Welsh, James W.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727581/
https://ncbi.nlm.nih.gov/pubmed/31484556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0718-6
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