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Vascularization, Oxygenation, and the Effect of Sunitinib Treatment in Pancreatic Ductal Adenocarcinoma Xenografts

The purpose of the study was to investigate vascularization, oxygenation, and the effect of sunitinib treatment in pancreatic ductal adenocarcinoma (PDAC). BxPC-3 and Capan-2 xenografts grown in dorsal window chambers were used as preclinical models of human PDAC. Tumor angiogenesis and the morpholo...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Gaustad, Jon-Vidar, Simonsen, Trude G., Wegner, Catherine S., Rofstad, Einar K.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727195/
https://ncbi.nlm.nih.gov/pubmed/31555596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00845
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