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Differential effects of hypothermia on neurovascular unit determine protective or toxic results: Toward optimized therapeutic hypothermia

Therapeutic hypothermia (TH) benefits survivors of cardiac arrest and neonatal hypoxic–ischemic injury and may benefit stroke patients. Large TH clinical trials, however, have shown mixed results. Given the substantial pre-clinical literature supporting TH, we explored possible mechanisms for clinic...

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Bibliographische Detailangaben
Veröffentlicht in:J Cereb Blood Flow Metab
Hauptverfasser: Lyden, Patrick D, Lamb, Jessica, Kothari, Shweta, Toossi, Shahed, Boitano, Paul, Rajput, Padmesh S
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727141/
https://ncbi.nlm.nih.gov/pubmed/30461327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X18814614
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