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Deactivation of mitochondrial complex I after hypoxia–ischemia in the immature brain

Mortality from perinatal hypoxic–ischemic (HI) brain injury reached 1.15 million worldwide in 2010 and is also a major factor for neurological disability in infants. HI directly influences the oxidative phosphorylation enzyme complexes in mitochondria, but the exact mechanism of HI-reoxygenation res...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Stepanova, Anna, Konrad, Csaba, Guerrero-Castillo, Sergio, Manfredi, Giovanni, Vannucci, Susan, Arnold, Susanne, Galkin, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727140/
https://ncbi.nlm.nih.gov/pubmed/29629602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X18770331
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