Transglutaminase 2 induces intrinsic EGFR-TKI resistance in NSCLC harboring EGFR sensitive mutations

The non-small cell lung cancer (NSCLC) patients with EGFR-sensitive mutations can be therapeutically treated by EGFR-TKI such as erlotinib and gefitinib. However, about 40% of individuals harboring EGFR-TKI sensitive mutations are still resistant to EGFR-TKI. And, it has been reported that both PTEN...

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Vydáno v:Am J Cancer Res
Hlavní autoři: Choi, Junyoung, Yoon, Shinkyo, Kim, Deokhoon, Moon, Yong Wha, Lee, Chang Hoon, Seo, Seyoung, Cheon, Jaekyung, Gho, Yong Song, Kim, Changhoon, Lee, Eung Ryoung, Kim, Soo-Youl, Lee, Kyoungmin, Ha, Joo Young, Park, Sook Ryun, Kim, Sang-We, Park, Kang-Seo, Lee, Dae Ho
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2019
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726998/
https://ncbi.nlm.nih.gov/pubmed/31497352
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