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Exercise Reduces Insulin Resistance in Type 2 Diabetes Mellitus via Mediating the lncRNA MALAT1/MicroRNA-382-3p/Resistin Axis

Insulin resistance (IR) is the primary pathological mechanism underlying type 2 diabetes mellitus (T2DM). Here, the study aimed to ascertain whether and how exercise mediates IR in T2DM. An in vivo mouse model of high-fat diet-induced IR and an in vitro high-glucose-induced IR model were constructed...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Liu, Sui-Xin, Zheng, Fan, Xie, Kang-Ling, Xie, Mu-Rong, Jiang, Ling-Jun, Cai, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726922/
https://ncbi.nlm.nih.gov/pubmed/31479923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.08.002
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